模型信息
中文名称:MERS-CoV HCoV-EMC/2012滴鼻,口腔,气管,眼途径联合感染狨猴模型
英文名称:MERS-CoV HCoV-EMC/2012 intranasally,orally,intratracheally and ocular infection common marmoset model
类型:MERS-CoV感染动物模型
分级:NA
用途:用于MERS-CoV感染研究。
研制单位:洛基山实验室@@http://www.niaid.nih.gov/about/rocky-mountain-laboratories
保存单位:洛基山实验室@@http://www.niaid.nih.gov/about/rocky-mountain-laboratories
研究背景
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制备方法
CoV strain EMC/2012 was performed intranasally (100 µl per nare), orally (500 µl), intratracheally (500 µl) and ocular (50 µl per eye) with DMEM containing 4x106 TCID50 MERSCoV/ml (total dose 5.2x106 TCID50).The hyperimmune plasma and monoclonal antibody groups, consisting of one female and two male common marmosets each, received 1 ml hyperimmune plasma or m336 diluted in PBS (5 mg/ml) intravenous (I.V.) at 6 hpi, and 1 ml hyperimmune plasma or m336 subcutaneous (S.C.) at 2 dpi.
评价验证
暂无介绍
生物安全性
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讨论与结论
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了解中析
实验室仪器
合作客户
